- Most populous nation not in the U.N.
- Most populous NATO member
- Most populous Nordic country
- Most populous of six states, for short
- Most populous of the United Arab Emirates
- Most populous OPEC nation
- Most populous place
- most populous republic
- Most populous Southern Hemisphere city
- Most populous state capital
- Most populous U.S. city that isn't a county seat
- Most poverty-stricken
- Most powerful club?
- Most powerful men on board, but not at court
- Most powerful piece in Stratego
- Most powerful primate
- Most powerful workstation
- most powerful, rich, or gifted members of a group
- Most precious
- Most precipitous
- Most preferred
- Most prestigious
- Most prestigious exemplar
- Most Prestwick Airport patrons
- Most pretentious
- most prevalent gas in air
- Most prevalent grape in Chianti
- Most pricey
- Most pricy
- Most priests
- Most prized
- Most prized, often
- most probably
- Most proficient
- Most profound
- Most profs
- Most prolific Hollywood actor, per IMDb
- Most prom attendees
- Most promgoers (Abbr.)
- most prominent
- Most prominent person in a field
- most prominent point at the back of the head
- Most prominent position
- Most promising
- Most promising slate of candidates
- Most promptly
- Most prone to be impudent
- Most prone to brooding
- Most prone to play "Grand Theft Auto V" and eat Doritos all day
- Most prone to preening
- Most prone to prying
- Most prone to sunburn
- Most protected
- Most provocative
- Most proximate
- Most prudent
- Most prudent, as advice
- Most prying
- Most pucker-inducing
- most puzzles heading
- Most qualified
- Most qualified to serve
- Most quick-to-learn
- Most quickly
- Most quirky
- Most racers, after the race
- most rapid
- Most rappers don't use them
- Most rare
- Most rational
- Most ready
- Most ready for picking
- Most ready for plucking
- Most ready for trouble
- Most ready to be picked
- Most real
- most real and correct
- Most reasonable
- most recent
- Most recent 007
- Most recent 600-homer club member
- Most recent box office arrival, probably
- most recent info
- most recent info with the
- Most recent news
- most recent or newest
- most recent or ultimate
- Most recently
- Most recently born
- Most recently introduced
- Most recently made
- Most recently produced
- Most recently released
- Most reckless
- Most recycled metal on Earth
- Most red
- Most red in the middle
- Most red, maybe
- Most reliable
- Most religiously homogeneous state in America
- Most remarkable person
- Most Rembrandts
- most remote
- Most remote from reputable
- Most remote, briefly
- Most repellent
- Most reprehensible
- Most repulsive
- Most reserved
- Most resourceful
- Most respected expert
- most respected person in a field
- Most respectful (of)
- Most restricted, filmwise
- Most ret. people
- Most retirees: Abbr.
- Most revealing
- Most revolting
- Most ridiculous, as an excuse
- Most rigid
- Most Ripleyesque
- Most robust
- Most rough-sounding
- Most rough, in a manner of speaking?
- Most rundown
- most rushed
- Most sacred
- Most sacred building in Islam
- Most sagacious
- Most sarcastic
- Most sarcastic, as remarks
- Most sardonic
- Most SAT takers
- Most saucy
- Most Saudis
- Most Saudis and Iraqis
- Most scant
- Most scantily dressed
- Most scanty
- Most scarce
- Most scorching
- Most scoutmasters
- Most scurrilous
- Most secure
- Most see-through
- Most seldom seen
- most self satisfied
- most self satistfied
- Most self-satisfied
- Most senators
- Most senior
- Most senior member of a group
- Most senior of two
- Most senseless
- Most sensible
- Most sensitive
- Most serene
- Most serious
- Most serious kind of flu
- Most serious, as a felony
- Most severe
- Most shaggy / Hotel offering / Actress Goldie
- Most shameful
- Most sharp
- Most sharply inclined
- Most sheltered
- Most shipshape
- Most shoddy
- Most sickly
- Most significant
- Most significant entitlement
- Most significantly, in texting
- Most silly
- Most silverware, actually
- Most similar to the Sahara
- Most simple
- Most sincere
- Most sinuous
- Most skilled
- Most skillful
- Most skittish
- Most sky-colored
- Most slapstick
- most sleazy
- Most sleepy
- Most slim
- Most slippery
- Most slow-witted
- Most slush pile responses
- Most small-minded
- Most smart
- Most smooth and lustrous
- Most smooth and stylish
- Most smooth, as peanut butter
- Most snarky
- Most sneaky
- Most snug
- Most Soc. Sec. beneficiaries
- Most Soc. Sec. recipients
- Most socially conscious
- Most soiled
- Most soldiers
- most solid
- Most sophisticated
- Most sordid
- Most sore
- MOST SORROWFUL
- Most sought-after party guests
- Most sound
- Most sound, mentally
- Most sour
- Most sour-tasting
- Most spacious
- Most spam
- Most spare
- Most sparse
- Most sparsely furnished
- Most sparsely populated Eur. country
- Most sparsely populated European country
- Most Spartan
- Most spick-and-span
- Most spicy
- Most spiders have eight
- Most spiffy
- Most spine-tingling
- Most sporting
- Most sports fans
- Most spotless
- Most spruce
- Most stable
- Most stale
- Most stale and moldy
- Most standoffish
- Most starfish have five
- Most state-of-the-art
- Most steaks
- most stern
- Most sticky, as a sweet treat
- Most stiffly proper
- Most stomach-turning
- Most straight, as wheels
- Most strange
- Most strapping
- Most stretched
- Most strict
- Most strongly built
- Most stuck-up
- Most student drivers
- Most Stuf cookie
- Most stylish