- First coat for a painter
- First coat of paint
- First coat of paint, sometimes
- First coeducational college in the U.S.
- first coin Roman
- First colony to defy Britain, 5/4/1776
- First color TV brand
- First color TV maker in the U.S.
- First column to add, usually
- first come first served
- FIRST come, first ___
- First coml. airline to show in-flight movies
- First commercial break, perhaps
- First commercial carrier to use the Boeing 747
- First commercial computer
- First commercial film shown in stereophonic sound
- First commercial film with stereophonic sound, 1940
- First commercial video game
- First commercially successful computer
- First company to be valued at $1 trillion
- First company to broadcast from the Empire State Building
- First company to create glow-in-the-dark underwear
- First company to successfully manufacture bubblegum
- first compartment of the stomach of ruminants
- First compass point, alphabetically
- First completed part of a jigsaw puzzle, often
- First computer company to run an ad during the Super Bowl
- First computer company with a Super Bowl commercial
- First computer to predict a U.S. election outcome
- First concern
- First conqueror of Everest with Edmund Hillary
- First corner after "Go" in Monopoly
- First correct "Hollywood Squares" spot
- First correct "Hollywood Squares" square
- First country in the world with universal suffrage (1906)
- First country to discover water on the moon
- First country to establish Christianity as its state religion
- First country to legally recognize same-sex unions
- First country you'd come to if you sail west from Mumbai
- First Couple home
- First couple's home
- First couple's place
- First Course
- First course
- first course of a meal
- First course of a sort
- First course of Action
- First course option
- First course option on a North African menu?
- First course selection
- First course with romaine and croutons
- First course, generally
- First course, maybe
- First course, often
- First course, perhaps
- First course, sometimes
- First course?
- First courses
- First courses, for short
- First cousin ___ removed
- First cousin of Prince William
- First cousin of Princes William and Harry
- First cousin twice removed, e.g.
- First cousin's father
- First cousin's mom
- First Cow cow
- First created
- First created being, in myth
- First creature found in a dictionary
- First creature off the ark
- First culprit
- First customer for the Boeing 787
- First cut on the album "Sticky Fingers"
- First czar of Russia
- First date concern
- First date no-no, for some
- First Daughter
- First daughter after Malia
- First Daughter after Sasha
- First daughter Carter
- First daughter Carter Actress
- First daughter in the '90s
- First daughter in the Carter White House
- First daughter of 1977-81
- First daughter of 1993-2001
- First Daughter of the '60s
- First daughter of the '90s
- First daughter of the 1970s
- First Daughter of the late 1970s
- First daughter, once
- First Daughter's full name
- First day of Lent
- First day of Lent: ___ Wednesday
- First day of spring, in Hanoi
- First day of spring, to Vietnamese
- First day of summer or winter
- First day of summer, e.g.
- first day of the month
- first day of the month in the Roman calendar
- First day of the rest of your life
- first day of the week
- First degrees (abbr.)
- First degs.
- First Derby-winning filly
- First digit
- First digit a toddler is taught, often
- First digit in a California ZIP code
- First digit in a Hawaiian zip code
- First digit in an Alaskan zip code
- first digit of the forelimb of amphibians, reptiles, birds, and mammals
- first digit on the hind foot of an animal
- First digital computer
- First director to win back-to-back Oscars since Mankiewicz
- First division of an act
- First division, maybe
- First divorced U.S. president
- First Dodge with front-wheel drive
- First dog in space
- First Dog of the forties
- First dog walker, maybe
- First Dominican major-league manager
- First Dominican manager in MLB history
- First Dominican manager in the major leagues
- First Dominican MLB manager Felipe
- First Dominican-born Major League Baseball manager
- First double-digit number
- First double, and first female, Nobelist
- First down?
- FIRST draft
- First draft of a 1995 De Niro/Pacino thriller?
- First draft of a movie
- First Dreamliner buyer
- First drink in aluminum cans
- First drive
- First dynasty of China
- First dynasty of imperial China, 221-206 B.C.
- First Earl of Avon
- First Earl of Beaconsfield
- First Earl of Chatham
- First earthly garden
- First ed.
- First Ed. Enclosure to an
- First edited version of a film
- first edition
- First editor of The Atlantic Monthly
- First Egyptian king
- First elected Congresswoman Jeannette
- First elected member at Cooperstown
- first elected member Cooperstown Info
- First electronic computer
- First electronic stock market
- First element
- first eleven
- FIRST emotion of love, flower symbolic of the
- First emperor of Rome
- First encounter in a romcom
- First English captain to sail round the world
- First entry in 'Who's Who in the Bible'
- First episode
- First episode in a TV series
- First episode of many a series
- First established
- First established position
- FIRST estate
- first european people to find a sea route to india
- First European to cross America
- First European to cross the Mississippi
- First European to discover Alaska
- first european to discover america
- First European to reach New Zealand
- First European to reach the Pacific
- First European to sail to India
- First European to see the Mississippi
- First ever public performance
- First eviction site
- First ex of Donald
- First ex of Donald and Ivana
- First ex-wife of Donald Trump
- First example
- First experience
- first experience of a difficult situation
- First explorer to sail directly from Europe to India
- First extra baseball inning
- First extra inning
- First fairy tale word
- First fall guy?
- first families
- First family brother
- First family father
- First family grandson?
- First family home
- First family member
- First Family member, 50 years ago
- First Family name
- First family of 1842
- First family of 1975
- First Family of 2010
- First family of Ferrara
- First family of Germany, 1969-74
- First family of the 1840s
- First family of the 1970s
- First Family of the 1980s
- First family Residence (abbr.)
- First family with the dogs Lucky and Rex
- First Family, 2001
- First family's address?
- First family's garden
- First family's garden site?
- First family's grandson
- First family's home
- First family's residence?
- First family's son
- First fatality
- First father
- First father-son Presidential surname
- First FBI director
- First fellow
- First felon
- First female
- First female Asian-American Cabinet member
- First female athlete to host "SNL"
- First female athlete to host Saturday Night Live
- First female attorney general
- First female candidate to win the Ames Straw Poll
- First female chancellor of Germany
- First female dean of Harvard Law
- First female dean of Harvard Law School
- First female House Speaker
- First female mathematician of the world
- First female member of Parliament
- First female Nobelist
- First female Nobelist, 1903
- First female prof at the Sorbonne
- First female recipient of the Cecil B. DeMille lifetime achievement award in film
- First female singer to have three simultaneous solo top 10 singles
- First female singer to have three simultaneous top 10 hits as a lead artist
- First female skater to land a triple/triple jump combination in competition
- First female solo artist in the Country Music Hall of Fame
- First female Sorbonne professor
- First female Speaker of the House
- First female supreme court justice
- First female to swim the Channel
- First female U.S. Attorney General
- First female U.S. secretary of state
- First female U.S. solicitor general, 2009
- first few
- First few bars
- First few bars of music
- First few chips, usually
- First few minutes of many podcasts