- ASC (Ambulatory surgery center)
- ASC+T (Anti Slip Control + Traction)
- ASCA (Annenberg Student Communication Association)
- ASCAP (American Society of Composers, Authors, and Publishers)
- ASCC (Alaskan System Coordination Council)
- ASCD (Association for Supervision and Curriculum Development)
- ASCDB (All Source Correlated Database)
- ASCDEDB (All Source Correlated Display Entity Database)
- ASCE (Association of Sound and Communication Engineers)
- ASCEPT (Australasian Society of Clinical & Experimental Pharmacologists and Toxicologists)
- ASCI (Assessments, Standards, Curriculum, and Instruction)
- ASCIE (All Service Combat Identification Evaluation)
- ASCIET (All Services Combat Identification Evaluation Team)
- ASCII (American Standard Code for Information Interchange)
- ASCLU (Associated Students of California Lutheran University)
- ASCM (Anti-Ship Cruise Missile)
- ASCMN (Area Signal Center Main Node)
- ASCO (Advanced Systems and Concepts Office)
- ASCOA (Antique Snowmobile Club of America)
- ASCOD (Austrian Spanish Co-operative Development)
- ASCON (Associated Contractors)
- ASCOPE (Areas, Structures, Capabilities, Organizations, People, and Events)
- ASCP (American Society for Clinical Pathology)